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Detection And Quality Control Of Host Proteins
Host proteins (HCP) form a major part of the process-related impurities in the production of biologics. The amount of residual HCP in a pharmaceutical product is often considered a critical quality attribute (CQA) because of its potential to affect product safety and efficacy.Aug.09, 2022Read More >
Definition And Structure Of Antibodies
Antibodies are shaped like the letter 'Y' and their main job is to bind to an invading antigen, but not to kill the antigen - they do not have this function; the binding is to give the antigen a marker to be destroyed. When phagocytes find the marker to destroy, they come forward and swallow the antibody-bound antigen and digest it.Aug.09, 2022Read More >
Selfish Bacterial Plasmids
Plasmids are a segment of circular DNA within a bacterium that is not part of the bacterial nuclear genome; they replicate within the cell and enter a daughter cell at random when it divides.Aug.09, 2022Read More >
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Fish ELISA Kits Types
E17C0027 Fish Cyclic Adenosine Monophosphate ELISA KitMANUAL
Cat. No.: E17C0027
Detection Range: 50-1000pmol/ml
Method: Competitive ELISA
Why Can Zebrafish Be Used As a Sample Model to Study Human Related Diseases?
Zebrafish have a high similarity of 87% with human genes, and their regeneration ability is very strong, so they are used in both retinal repair and auditory repair. In immunology, adult zebrafish can survive without the generation of thymus and lymphocytes. The zebrafish in early embryonic development after Escherichia coli infection is locally cleared by macrophages, which suggests that there may also be a cytokine or chemokine system similar to that of mammals in zebrafish. In addition, zebrafish, as a model organism, their development, function, and diseases (such as nervous system, immune system, cardiovascular system, reproductive system, etc.) in various systems (such as neurodegenerative diseases, hereditary cardiovascular diseases, diabetes, etc.) are deeply studied.
What Are the Precautions when Taking Fish Samples?
Taking zebrafish as an example, they live in water temperatures between 20℃ and 23 ℃. Feed Artemia regularly one week before the experiment and observe the clarity of the water in the water tank in time. The zebrafish has a strong circadian rhythm. And it is necessary to pay attention to switching on the light at 8 am and off at 10 pm. Due to the small body sizes, they should be soft to hold during the operation. After the operation, it should be treated with ice-freezing anesthesia. In addition, zebrafish have less blood with the blood color light blue or colorless. In the immunoassay, there are a few body fluid samples, which can be cut into pieces, broken and mixed by the homogenizer, and then centrifuged to take supernatant samples.