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BlueGene Biotech News Center

  • Detection And Quality Control Of Host Proteins

    Host proteins (HCP) form a major part of the process-related impurities in the production of biologics. The amount of residual HCP in a pharmaceutical product is often considered a critical quality attribute (CQA) because of its potential to affect product safety and efficacy.

    Aug.09, 2022
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  • Definition And Structure Of Antibodies

    Antibodies are shaped like the letter 'Y' and their main job is to bind to an invading antigen, but not to kill the antigen - they do not have this function; the binding is to give the antigen a marker to be destroyed. When phagocytes find the marker to destroy, they come forward and swallow the antibody-bound antigen and digest it.

    Aug.09, 2022
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  • Selfish Bacterial Plasmids

    Plasmids are a segment of circular DNA within a bacterium that is not part of the bacterial nuclear genome; they replicate within the cell and enter a daughter cell at random when it divides.

    Aug.09, 2022
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BlueGene Biotech's Research For Signal Transduction


1. Definition Of Signal Transduction

It is known that there are many signal transduction modes and pathways in cells, and there are multiple levels of cross-regulation between them. It is a very complex network system. In short, a process in which various signals can enter the cell through the cell membrane and gradually cause changes in cellular substances, mainly proteins, is called signal transduction. It is a multi-enzyme cascade reaction process. Each signal pathway forms a highly ordered regulatory network in vivo through the interaction of intercellular signal proteins. 


2. Mammals & Signal Transduction

Mammals need a variety of signal transduction pathways to maintain the integrity and coordination of cell response to signal stimulation. There are mainly six kinds of transmitters responsible for extracellular signal transduction to the interior of cells. They include ion channel gates, receptor enzymes, serpentine receptors, steroid receptors, adhesion receptors, and receptors themselves that do not contain enzymes.