Detection of Cytokines
Cytokines have been shown to be involved in important physiological activities such as immune regulation and inflammatory response, tissue repair, stimulation of the hematopoietic system, stimulation of cell proliferation and apoptosis, and play an important role in resisting foreign pathogens and maintaining the balance of the body's internal environment.
The clinical applications of cytokines mainly include:
Participating in the inflammatory response caused by infection, such as TNF-α, IL-1, IL-6, IL-8, etc.;
Promoting tumor cell growth and metastasis, such as TNF -β, IL-10, IL-6, etc.;
Mediate transplant rejection, such as IL-2, IFN-γ, etc.;
Mediate immune diseases: ①Immune deficiency, such as IL-2 receptor γ chain gene (X chromosome) mutation → IL-2, IL-4, IL-7, IL-9 and IL-15, and other cytokines dysfunction; ② hypersensitivity reactions, such as IL-4, IFN-γ, and other cytokines; ③ autoimmune diseases, such as IFN-γ, IL-2, and other cytokines.
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